Deferiprone is a medicine which is used in removing excess iron from the body in people who have beta-thalassaemia major. Deferiprone belongs to a class of medicines called chelating agents. Buy deferiprone 500mg tablets on discount price is used if you have trouble taking other traditional iron-removal medications or you continue to have high iron levels after taking other iron-removal medications.
However, if you realize that you have missed a dose when it is almost time for your next dose; do not take two tablets together. This may result in an overdose. Doses of 50-120 mg/kg/day appear to be effective in bringing patients to negative iron balance. Deferiprone increases urinary iron excretion, which mainly depends on the iron load of patients and the dose of the drug.
Deferiprone Tablet Dosage, Uses and Side Effects
It is used to treat thalassaemia major. Deferiprone is only used when other treatments are not suitable or have not been successful. Ferripox (Deferiprone) 200mg is used by people with a certain type of blood disorder (thalassemia) who have too much iron in the body, caused by repeated blood transfusions. Blood transfusions help people with blood disorders but they also bring extra iron into the body. It is important to get rid of the extra iron because high levels of iron can cause health problems (such as heart failure, liver disease, diabetes, delayed growth in children).
Our brand name is Defthal (deferiprone). Defthal (defriprone) capsule is available in 250 500mg. Packing as per the choice of the party. Ferripox (Deferiprone) 200mg belongs to a class of drugs known as iron chelators. It works by attaching to iron which helps your body pass the extra iron out in the urine. Deferiprone (100 mg/kg) reduces the mean basilar artery cross-sectional areas by 24% in rabbits. Deferiprone (100 mg/kg) combined with subarachnoid hemorrhage(SAH) shows a variable amount of corrugation of the internal elastic lamina in rabbits.
Deferiprone brands in india is an oral medication primarily consisting of deferiprone. Deferiprone is a synthetic iron chelating agent. Each deferiprone tablet contains about 500 mg of deferiprone. Deferiprone is a white-pinkish crystalline substance which is partly soluble in liquids. deferiprone tablets are capsule shaped and white to off white in colour. Other inactive ingredients found in deferiprone include – microcrystalline cellulose, magnesium stearate, colloidal silicon dioxide, methyl cellulose, polyethylene glycol and titanium dioxide.
Deferiprone 500mg tablets are normally prescribed to patients suffering from iron overload. Iron overload is usually observed in patients suffering from Thalassemia. It isn’t necessary that every Thalassemic patient will be prescribed deferiprone. Depending on a patient’s case history and illness, deferiprone may be administered if the chelation therapy that the patient is undergoing proves to be inadequate. Thalassemic patients are always under strict observation and undergo regular tests. When doctors find increased iron content in their bodies, they are immediately prescribed iron chelating agents.
Deferiprone Mechanism Of Action
The drug has a chelating effect that causes it to be attracted to ferric iron ions. It binds to the iron which is a type of selective process that is unique to this medication. Neutral 3:1 levels of Deferiprone to iron complexes form which are stable over a variety of pH values.
Deferiprone is not as highly attracted to aluminium, copper or zinc. The binding effect flushes excess iron from the body through urination while having less of an effect on other metals.
Deferiprone Solubility
Deferiprone solubility in water is 293.2; in ethanol 298.2; and N=Methyl-2-pyrrodlidone 303.2. In non-water based mixtures, Deferiprone is a class 4 pyridone with pyridin 4 (1H) 1 substituted and 1 and 2 positions by methyl groups, with the 3 position by a hydroxy group. This drug is lipid soluble, also referred to as fat soluble.
Lipid soluble substances have the ability to pass through the cell membrane with greater ease than water solubles. Molecules diffuse through the lipid bilayer without interference by hydrophobic fatty acid chains.
The good news is that this drug is more quickly absorbed into the body and it goes to work faster than water soluble medications.
Availability
There are many online pharmacies that are out of stock of Deferiprone or Ferriprox. This will not be the case for us. We understand that this medication is vital for preserving the health of people for whom this is recommended.
We always keep Kelfer in stock. This product is not slated for discontinuation so you can rest assured that when you need to place your order, it will be processed in a timely manner.
The benefits of Kelfer 500 mg over Ferriprox 500 mg
Iron chelators are often very expensive. The name brand, Ferriprox can be too expensive for many people who are either under-insured or who have no health care insurance, to afford. We are doing our part to help put the medications that people need to improve their health within reach.
Is Kelfer from India safe?
Yes. There is no difference in the ingredients which are used for CIPLA generics and the more expensive name brand drugs. There are always risks associated with drugs and supplements, but our generics are made with quality raw materials. There is no difference in the way that Kelfer performs when compared to Ferriprox. Kelfer is as safe as Ferriprox.
Deferiprone manufacturer
CIPLA is one of the largest manufacturers of pharmaceuticals in the world. They procure the raw materials from India, which are the same ingredients used in the more expensive brand name drugs sold in the US and other countries.
The quality of the materials is no different than higher priced brands and the formulation is the same so as a consumer, you are getting the same product under a different name at a lower price.
Deferiprone is usually administered daily. The recommended dosage is usually 25 mg, three times a day – a total of 75 mg per day. deferiprone price Depending on the seriousness of a patient’s condition, higher doses up to 33mg per dose may also be administered. Dosages vary depending on a patient’s response to treatment and other medical symptoms. If a patient does not seem to be getting better, doctors may increase the recommended dosage or change the medication. The maximum recommended dosage is usually 99mg per day. Higher dosages may result in further complications.
If you miss a dose it is important to inform your doctor immediately. Although patients may not experience any immediate physical difficulty after missing a dose, their iron levels may fluctuate resulting in health problems later. Minor symptoms like weakness, sudden changes in blood pressure, dizziness and drowsiness may occur if you miss a dose. When you realize that you have missed a dose, it is important to have a replacement tablet within the next few hours.
Deferiprone cost is an orphan drug designed and developed primarily by academic initiatives for the treatment of iron overload in thalassaemia. Deferiprone has been used in several other iron or other metal imbalance conditions and has prospects of wider clinical applications. Deferiprone has high affinity for iron and interacts with almost all the iron pools at the molecular, cellular, tissue and organ levels.